KDM5A-GATAD1-EMSY Chromatin Complex and Disease (P23819)

Target Name: KDM5A-GATAD1-EMSY chromatin complex

NCBI ID: P23819

Other Name(s): None

KDM5A-GATAD1-EMSY Chromatin Complex and Disease

The KDM5A-GATAD1-EMSY chromatin complex is a protein complex that is involved in the regulation of gene expression and DNA replication. The complex consists of three proteins: KDM5A, GATAD1, and EMSY, and is typically found in the nucleus of the cell.

KDM5A is a histone-remodeling enzyme that uses ATP to remove the negative electrostatic effects of histone tails and to reposition them along the DNA. This process is important for the proper structure and function of the chromatin complex.

GATAD1 is a non-histone protein that is involved in the regulation of DNA replication and repair. It helps to ensure that the correct copy of the genetic information is passed on to the cell's two daughter cells.

EMSY is a non-histone protein that is involved in the regulation of gene expression. It helps to ensure that the cell's genetic information is properly copied and translated into proteins.

The KDM5A-GATAD1-EMSY chromatin complex plays a crucial role in the regulation of gene expression and DNA replication. It helps to ensure that the cell's genetic information is properly copied and translated into proteins, and that the structure of the chromatin complex is properly maintained.

GATAD1 and EMSY are known to have been implicated in the development of certain diseases, such as cancer. This is because they are involved in the regulation of important cellular processes, and changes in their function can have a significant impact on the health and survival of the cell.

KDM5A is also known to have been implicated in the development of certain diseases, such as Alzheimer's disease. This is because it is involved in the regulation of important cellular processes, and changes in its function can have a significant impact on the health and survival of the cell.

In conclusion, the KDM5A-GATAD1-EMSY chromatin complex is a protein complex that is involved in the regulation of gene expression and DNA replication. It is made up of three proteins: KDM5A, GATAD1, and EMSY, and is typically found in the nucleus of the cell. GATAD1 and EMSY are known to have been implicated in the development of certain diseases, such as cancer and Alzheimer's disease, and KDM5A is also known to have been implicated in the development of certain diseases, such as Alzheimer's disease. Therefore, the KDM5A-GATAD1-EMSY chromatin complex may be a drug target or biomarker for the development of certain diseases.

Protein Name: KDM5A-GATAD1-EMSY Chromatin Complex

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